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What Are Causes of Nasal Polyps ?

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The pathogenesis of nasal polyposis is unknown. Polyp development has been linked to chronic inflammation, autonomic nervous system dysfunction, and genetic predisposition. Most theories consider polyps to be the ultimate manifestation of chronic inflammation; therefore, conditions leading to chronic inflammation in the nasal cavity can lead to nasal polyps. The following conditions are associated with multiple benign polyps:  -Bronchial asthma - In 20-50% of patients with polyps -CF - Polyps in 6-44% of patients with CF [1] -Allergic rhinitis -AFS - Polyps in 85% of patients with AFS -Chronic rhinosinusitis -Primary ciliary dyskinesia -Aspirin intolerance - In 8-26% of patients with polyps -Alcohol intolerance - In 50% of patients with nasal polyps -Churg-Strauss syndrome - Nasal polyps in 50% of patients with Churg-Strauss syndrome -Young syndrome (ie, chronic sinusitis, nasal polyposis, azoospermia) -Nonallergic rhinitis with eosinophilia syndrome (NARES) - Nasal polyps in 20% o...